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Martin Gauster, PhD:

Placenta-derived cytokines and chemokines in maternal leukocyte activation

Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Chair of Cell Biology, Histology and Embryology, Medical University of Graz, Neue Stiftingtalstraße 6/II, A-8010 Graz;
phone: +43-316-385 71896, fax: +43-316-380 79612, ✉ e-mail
• Profile     • Curriculum vitae     • PhD students     • Grants     • Publications ⏬    

List of publications:

10 most significant publications:

  1. Gauster M, Maninger S, Siwetz M, Deutsch A, El-Heliebi A, Kolb-Lenz D, Hiden U, Desoye G5 Herse F, Prokesch A: Downregulation of p53 drives autophagy during human trophoblast differentiation. Cell Mol Life Sci, 2018; 75(10):1839–1855.
  2. Siwetz M, Blaschitz A, El-Heliebi A, Hiden U, Desoye G, Huppertz B, Gauster M: TNF-α alters the inflammatory secretion profile of human first trimester placenta. Lab Invest, 2016; 96(4):428–438.
  3. Siwetz M, Dieber-Rotheneder M, Cervar-Zivkovic M, Kummer D, Kremshofer J, Weiss G, Herse F, Huppertz B, Gauster M: Placental fractalkine is up-regulated in severe early-onset pre-eclampsia. Am J Pathol, 2015; 185(5):1334–1343.
  4. Siwetz M, Sundl M, Kolb D, Hiden U, Herse F, Huppertz B, Gauster M: Placental fractalkine mediates adhesion of THP-1 monocytes to villous trophoblast. Histochem Cell Biol, 2015; 143(6):565–574.
  5. Siwetz M, Blaschitz A, Kremshofer J, Bilic J, Desoye G, Huppertz B, Gauster M: Metalloprotease dependent release of placenta derived fractalkine. Mediators Inflamm, 2014; 839290.
  6. Gauster M, Hiden U, van Poppel M, Frank S, Wadsack C, Hauguel-de Mouzon S, Desoye G: Dysregulation of placental endothelial lipase in obese women with gestational diabetes mellitus. Diabetes, 2011; 60(10):2457–2464.
  7. Gauster M, Siwetz M, Orendi K, Moser G, Desoye G, Huppertz B: Caspases rather than calpains mediate remodelling of the fodrin skeleton during human placental trophoblast fusion. Cell Death Differ, 2010; 17(2):336–345.
  8. Gauster M, Hiden U, Blaschitz A, Frank S, Lang U, Alvino G, Cetin I, Desoye G, Wadsack C: Dysregulation of placental endothelial lipase and lipoprotein lipase in intrauterine growth-restricted pregnancies. J Clin Endocrinol Metab, 2007; 92(6):2256–2263.
  9. Gauster M, Rechberger G, Sovic A, Hörl G, Steyrer E, Sattler W, Frank S: Endothelial lipase releases saturated and unsaturated fatty acids of high density lipoprotein phosphatidylcholine. J Lipid Res, 2005; 46(7):1517–1525.
  10. Gauster M, Hrzenjak A, Schick K, Frank S: Endothelial lipase is inactivated upon cleavage by the members of the proprotein convertase family. J Lipid Res, 2005; 46(5):977–987.

29.05.2018 DP-iDP Doctoral Programme “Inflammatory Disorders in Pregnancy”